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Thanks so muchCould be an intestinal worm, he’s not eating at all?
If he isn’t eating, you could try dosing prazipro. It is *relatively* reef safe, but you have to be careful to keep the tank well-aerated and if you have a large feather-duster or bristle-worm population could be problematic. Also, be very careful not to over-dose, keeping displacement from rocks/corals/sand etc in mind.
If dosing prazi gets him feeling well enough to start eating again, then you can switch to General Cure + Focus soaked food.
Internal Pathogens
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I’ve never used it with Prazi, personally. It’s ok to use with antibiotics when no copper is present, but in general it’s better to use Bio-Spira or similar instead since Prime is more of a bandaid anyway.