Im sure one of these would still benefit your aquarium, it would still provide lots of room for bacteria to grow. It just wouldn't be as efficient as it would be with carbon. People dose carbon to help bacteria thrive but lots of people have great tanks without carbon dosing.
The benifits doesn't end on nutrient control only, excess bacteria in the reactor will feed your corals and filter feeders too. Try a few ml more on your normal dosage, half an hour before lights out. Your corals (sps especially) will go into feeding frenzy with all the bacteria oozing out from reactor. With skimmer, it might not work for you. I don't run a skimmer, my corals act as a skimmer