At this point, if the lesion is growing, I would treat with copper and an antibiotic. If it isn't growing, I'd stick with just the copper.
Uronema grows intercellularly, so there really is no effective treatment once it gets going. While it is pretty common in new chromis, it also is ubiquitous, it can be isolated from many aquariums. It normally just feeds on bacteria. For some reason, it becomes an internal parasite to new chromis, wrasses and anthias. It isn't anything you need to tear a tank down about, just avoid the problem species for some time.
In terms of antibiotics - you want to use a broad spectrum, gram negative one, like Neoplex or Furan-2.
Jay
Sounds like a plan, thank you for your help, @Jay Hemdal!