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Not a scientist, but wouldn’t the way to really hammer down any of the color changing tests to super low levels be to take our raw observation of the colored result out and stick it in front of an optical sensor hooked up to a computer instead? A sensor would be able to pick up the subtle changes in available light passing through of certain spectrums based on the variations in the color of the test result. That could then be correlated to a numbered scale to get your super low results.