Generally not, at least not at the same rate.
We still don't know precisely why they fail, but based on what people like
@UncommonSense have reported when disassembling failed tanks it appears to be a silicone issue. Basically, for whatever reason the silicone that Red Sea uses isn't nearly as strong as it should be, and under the higher pressure exerted by a larger tank, it fails.
That's not as big of an issue in a small tank. In a larger tank with a bigger footprint (say, 48 x 21 for the front pane of a Reefer 350), the silicone has to hold against about 750 pounds of pressure. On a smaller tank, the front pane (23 x 18, for the Nano Max peninsula) the silicone only has to hold up against about 270 pounds. That's a lot easier for even Red Sea's weaker silicone. Full disclosure, I just did some quick napkin math for those figures, the actual value may be different.
Personally I still wouldn't, but that's because I don't really like Red Sea as a company. But from a strictly safety point of view, I don't think the nanos have had the same problems as the Reefers.
Other people with actual experience with the nanos can of course correct me if I'm wrong.
