You sure can. See this...https://www.bulkreefsupply.com/brs-biopellet-reactor.html I don't know if you will need additional fittings or not and you will have to remove the sponges. Contact BRS and find out. They have always been very helpful. Or you can just but the one made for Bio pellets if you haven't already purchased. I can't see much difference in the descriptions.