A refugium is any tank or part of a tank free of predators. It can be lit or dark. Normally people grow macro algae in them as it is a great means of nutrient export. I have run both types with success. Mandarins need lots of pods and the back of a bio cube might not be able to sustain a large enough population for that fish. If you really want one I would suggest a bigger tank or culture pods/buy live pods.