Palytoxin Question

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Shep

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In your opinion as a chemist do you think a palytoxin toxoid or a recombinant catalytically inactive palytoxin would work best for a vaccine? Doing a research project for one of my grad classes and figured I would ask the reef chemist expert lol
 
I would think it would depend on how you inactivated the palytoxin and what recombination you did you reduce catalytic activity, but I'd prefer to develop the latter, even if it might be more complicated. It is likely more reproducible.
 
Thanks, thats what I was thinking, plus it would keep the native shape.
 

WHAT KIND OF SUBSTRATE ARE YOU RUNNING ON YOUR TANK?

  • Bare bottom

    Votes: 5 22.7%
  • A shallow bed of fine sand

    Votes: 5 22.7%
  • A shallow bed of coarser sand

    Votes: 4 18.2%
  • A deep sand bed

    Votes: 3 13.6%
  • Mixed substrate or varying sand depth

    Votes: 5 22.7%
  • Some other substrate (posted in the comments)

    Votes: 0 0.0%
  • I don’t have a reef tank yet

    Votes: 0 0.0%
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