I developed a horrible aptaisia infestation in my 110 gal FOWLR tank. I already had a lazy matted filefish that let the invasion spread unchecked. I added a small threadfin butterflyfish, and the result was incredible. I've always kind of suspected that claims that "This fish cleaned out a tankful of aptaisia in a few days." were possibly slightly exaggerated. This guy really did it! It's slightly aggressive and has held it's own with the world's nastiest Whitetail Bristletooth Tang, Harlequin Tusk, a large dogface puffer, a large Foxface, an aggressive Clarki Clown, and an adult Zebra Eel. My remote fuge is an aptaisia factory, but after about a year, there's still not one in the display. I understand they're not considered reef friendly, but I don't have any experience of how damaging they can be.