Healthy caution, I think is the statement I would use. As long as you are not fragging them, mishandling them, and washing your hands after handling them, then you will be fine. Also avoid fluids to the eyes, or mouth.
Some are very toxic, but as long as they are in water they are safe. If you touch them wash your hands, if you pull them out of water wear gloves and a eye protection or better yet a face shield just so your mouth is covered too.