Sure i have a 29 gallon corallife biocube with 180watt leds about 15 pounds of live rock, 2 inch sand bed wich i vaccum all the time i also use a turkey pastor to blow the ditritus out of the rocks. The biocube skimmer wich isnt the best but better than nothing, stock biocube pump,a 500 gph power head. Filter floss, carbon bag and purigen.