Yes.. but I've been told not too
Let’s clarify that, since on its face, it is nonsensical to dose NOPOX if one believes that dosing the individual components in it is a problem.
NOPOX is mostly ethanol and acetic acid. Ethanol is the component in vodka. Acetic acid is the component in vinegar. NOPOX also contains a small amount of isopropanol and methanol, which I suspect are there to make the ethanol undrinkable and thus untaxed (it’s called denatured ethanol or denatured alcohol) rather than for any in tank benefit.
There may be reasons to not dose organics at all, including lowering of pH, O2, and changes to bacterial populations that could possibly be pathogenic to corals.
There are also reasons to dose organics beyond nitrate lowering, such as the increased bacteria being food for many types of filter feeders including corals. Many organisms, including corals, may also directly use the organics as a food.
So on balance, there are pros and cons, and they apply equally to commercial products such as NOPOX or diy recipes made with the same ingredients.
I used vinegar for years and slightly preferred it it my tank to vodka, but that may depend entirely on which microorganisms are present in the tank.
At the moment, I need to dose N, so organic carbon dosing is not part of my current husbandry.