Has there been any research done in how these bacteria and enzyme stains actually reproduce? Specifically, for my use case, Microbactor 7 & Clean, as well as, "reef muds" such as AF Life Source & Miracle Mud. All of these products claim to require continual dosing in order to remain effective. MB7 claims to be a dormant bacteria and enzyme blend which is unable to reproduce in our home tanks. MB Clean claims that the bacteria are cystic and, as well as the enzymes. are also unable to reproduce in our tanks. Is there an outlying factor that would cause these specific strains to not be able to reproduce in the home environment? Furthermore, reef mud products also recommend dosing weekly, but after the recent BRS series, It would seem that you would only need to dose once in order to get the beneficial biodiversity that they offer.