Naturally, I want to do it. I have dinos I'd like to get rid of. Whether efficacy drops to nil without the housing and pump, I don't know. If the downsides of running the bulb in the chamber are very low compared to the upside of it having some effect, I would just leave it on over the weekend. However, if the downsides include any notable damage to the AIO chamber, I'd say that's a No-Go. I still don't think we have a material answer to that question.
I don't think we can make a blanket statement about the efficacy of the unit outside of the housing. Sure, it brings the water and microbes closer to the bulb. It pumps the water through slower than the overflow passes the water so that it has longer contact. But that proximity MAY not be necessary. I run UV lights in my laminar flow hoods for sterilization:
This is, of course different. The matrix is air and not saltwater. The microbes are constantly exposed instead of briefly and repeatedly. But they certainly aren't very close to the bulb.
I've been running the bulb free of the housing for about 4 hours today. The tank has gone from something like this (earlier picture, it was covering all parts of the glass today):
to this currently:
I don't know if this is a temporary effect from blowing off the rocks/scaping the glass, or if the UV is having an effect. The last time I blew off the dinos, it reformed and settled again rapidly. ¯\_(ツ)_/¯
Is it wise to do this? No, probably not wise to stray from manufacturer's instructions. Is it reckless? That, I don't know and was hoping to be informed.
I think this discussion has led me to turn it off over the weekend just to be safe. So this is not a "validate my position // do it anyway" post. I appreciate everyone's input and offers for help!