I would stick with a bunch of hermit crabs with small volumes of water and have ten or so different sets of variations of the water thereby are kept in. High salinity, low salinity, water that’s comprised some way with either amonia, nitrates or other pollution such as lotion, or low O2 and observe the effects. The only thing you would need to keep up would be the evaporation. It’s not lab science but would be enough to document cause and effect. It would be inevitable you would have losses but in the name of science :)