I had to use Interceptor for red bugs about 3 months ago and I was worried about the same thing as well as a fire shrimp, coral banded shrimp, and peppermint.. I have two with gobies in different locations in my 120G (100 G volume). I finally made the decision to run the interceptor rather than tear the tank apart. I went very conservative on the amount I used and when for the traditional 6 hours treatment. It killed all my redbugs, 1 hermit crab, and a few bristleworms, but I didn't lose any shrimp. It also wiped out the redbugs. I was planning to do a follow up treatment, but when I noticed all redbugs were gone over the following weeks, I decided to pass on it. 2 months later, all shrimp alive, all redbugs dead.