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If it’s any help, I went through the same thing several months ago with my 75 gallon tank. My LFS recommended treating the water with Seachems Metroplex dosed to the tank and then add it to the fishes food along with Seachems focus. You may also want to add some garlic to the food. Fish will not eat metroplex in the food without the Focus and Garlic. After about 3 weeks ick was gone and has not returned in 10 weeks since. I also stopped loosing fish once I started dosing. I have since setup a QT, and purchased a Grren Machine UV Sterilizer from Amazon (Much cheaper than what you’ll find at the LFS and works great. I have mine in the sump.