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Yes, it is safe. Fluconazole does not reach any major metabolic pathway of any animal in the aquarium at the recommended doses.Does anyone know if this treatment is safe for clams?
The term GHA does not refer to a species of algae, but to many species that present themselves in a similar way (filamentous form). Filamentous algae, in relation to their cellular structure, may be unicellular or siphonous algae (such as Derbesia and Bryopsis), or multicellular algae (such as Cladophoropsis and Cladophora) and many others, these are also commonly called "turf algae" ... siphonous algae are frequently sensitive to Fluconazole, the rest may not be sensitive at the recommended doses.Nobody really responded to my question I posted earlier. I am 3 days in to a treatment for GHA, and it is still persistent. It definitely seems less dense , but I think it may be growing in new spots. I see it in the sand , is it falling off the rock and getting stuck? It seems longer in spots than before which is irritating some corals, is this because the structure is stretching? I do see some algae on my powerheads that wasn't there before. Is it possible for any algae to grow in a tank with Fluconazole? I went from scraping the glass 3-4 times a week to 2 times a week.
I added another 400mg yesterday (32 gallon tank), so I have a double dose. Reef HD says they have used 10X the dosage without issue. Everything seems to be doing fine and I am getting growth on several corals, but the persistant GHA is really bumming me out. It affects my zoas the most. I have 2 colonies that are alive but don't open because of the irritation of the gha.
I know that GHA takes longer to battle, but how long should I expect?
As for the time the action of fluconazole is perceived, it varies from 4 days to 1 week, when you begin to notice that the algae lose color, usually beginning at the tips, and begin to break loose or to be attacked by herbivores that before they despised them.
Regards
If there have already been changes, you are likely to be able to eliminate them, and it is only a matter of time.I have definitely noticed some die-off and color change (more of a brown than green) and texture change, so it is doing something. I guess I will see what happens at 2X dosage.
Also note that if I were using Fluconazole to treat my fish for infections I would need to dose this same amount every 24hrs for no less than 5 days but not more than 10 days.
ThanksYes, it is safe. Fluconazole does not reach any major metabolic pathway of any animal in the aquarium at the recommended doses.
Regards
The theory says yes, because the Caulerpales (the whole family) have ergosterol in their cell walls, and this makes them sensitive to the effects of fluconazole. But because they are slow growing and because they have thick walls, the time and doses needed to eradicating them are greater than the time and doses required for Bryopsis and Derbésia. Maybe double or more, depending on what kind.Any one try this for Caulerpa? Did it work?
By the filament format, with little branching and no "feather" pattern, most likely it is not Bryopsis, but may be Derbesia, which is also quite sensitive to fluconazole, or another species of GHA (Cladophora, Cladophoropsis and a broad etc) , which may be very resistant or not sensitive to fluconazole at the usual doses.Good day all. I’m on my 5 day of using 9mg/l fluconazol but not seeing much effect. Please confirm I am indeed dealing with bryopsis.
The way the pharmaceutical form is made ("modus faciendi", in technical jargon), is extremely important in its pharmacokinetics (how it dissolves, distributes and acts). A formulation of fluconazole can fulfill its purpose for human or veterinary medical use and, even then, does not obtain good results in the environment of an aquarium, for algae control.I bought my first batch from Payless Pet Products for my GHA. I seem to be the only one who got tablets instead of capsules. I bought a pill grinder which did a pretty good job. I did the normal 20mg/gal dose. After 2 weeks of seeing very little change (maybe actually getting more growth in places), I added another 20g/gal dose. I let this sit for another 10 days or so with no change. At that point, my kenya tree stopped extending and my trachy wasn't really inflating. Nutrients were all still low. The kenya tree had a film on it, maybe the binder from the tablets??
I ordered some reef flux (which I knew were capsules), turned the skimmer on, added carbon and purigen (Reef HD says to use purigen to remove fluco). I did four 5 gallon WC (tank is 32 gallons) over 4 days. I then added the reef flux (4 capsules) and started dosing vibrant. I felt that if the GHA may be fluco resistant, the vibrant may attack a different strain. After 2 days of this, I was seeing better results. The GHA was clumping, and looked like it was melting in places.
I'll keep on dosing vibrant 2X a week, and leave the fluco in the tank. This is frustrating and disheartening to be honest. I'll keep monitoring the nutrients.
Did I get expired or crap fluco from Payless?? It was clearly black market tablets.
Where can i order this great research thankx
Over several months I have done this procedure. After the 14-21 day mark, my tank is pretty and all is well.
For a month or so, if not a shorter time frame.
After the month, the Bry all comes back, slowly but surely. It comes back stronger than before, as well as in new places.
I have continued to dose after this happens. It's an ongoing thing for a temporary clean tank.
Does anyone else run in to this issue? The Flucon definitely works, but doesn't get rid of the issue for good. For me anyhow
And yes, I have done treatments back to back, and had same result. I have also done treatments, back to back to back. same result with the month later, its all back