I have a 125 with an epaulette shark 26 inch and tessalatta eel 22 inch and that's it. I run a protein skimmer rated fo a 220 and I still have algae on my glass with biweekly w/c. My guy and gal are super healthy and growing quickly and so now t my point. I thought I would be able to upgrade yearly and I have upgraded just a few months back to the current 125. However im already thinking cost effective and to be honest I would go bigger first other wise you are gonna spend a few thousand first, then 5 thousand, then for a sweet full blown predator at 10 ft long, 5 ft front to back, and 18 inch tall like im doing for sharks, rays, and puffers then you will sped like 8-12k....in the long run find a really great big set up on CL or r2r and go ith it because otherwise you will spend a fortune on upgrading tanks, lights, and filtration not to mention having to recycle tank every so often and adding rock when doing so that's new to keep rock/water volume ratio right. This has been my experience every step of the way and its best to take your time like im going to do with my LAST upgrade so I don't have to again :)