A few things. First of all, your pump has a 1.25" outlet. I would up-size it to 1.5" to reduce friction loss as much as possible. Use swept 90, or dual 45's for each turn. Line locs are fine, but you will get a lot of friction from them, unless you keep the plumbing large and only reduce it right before it goes into each unit. Next, is head pressure. If the inlet end of the pump and the outlet end of the pump are both in the display, you do not have to worry about vertical distance. Think about it. If you shut off your return pump, what does it do? It siphons back into the sump until it draws in air and breaks the siphon. If you cut off your closed loop pump, what does the water do? Nothing, it just stops, because there isn't any water height difference between the inlet and outlet. The only thing that creates head pressure at that point is the friction loss from the plumbing. Again, oversize the plumbing and don't use standard 90's...ever...One more comment...the way they calculate flow for a power head and how they calculate flow for an inline pump are completely different. For a powerhead, they put the powerhead in water and use a device to measure water velocity in a 3d grid all round the power head, then calculate total flow. This calculates how much water is actually being moved around in the tank. For an inline pump, they measure the velocity of water inside the outlet pipe, and from that, using a specific plumbing size, calculate how much water is flowing through the pipe. The problem with this is that it isn't apples to apples. When the water comes out of a plumbing outlet, it creates an area of low pressure behind the edge of the pipe that draws in water from around the outlet, moving more water than just what was inside the pipe. People don't use closed loops much anymore, so no one has taken the time to calculate them, but I can say with confidence that 3000 GPH coming out of a pipe will produce a lot more in tank flow than a powerhead rated at 3000 GPH. So keep that in mind when trying to estimate your total system turnover. For a 300DD, I would start with atleast 2 DC style pumps. 2 Ecotech L2 pumps would be a good place to start and as it fills in, you may need to add more...