Fast moving pathogen. What is it?

[wangspeed]

My best guess is uronema, but this is really fast. As in I got this replacement lineatus wrasse in from LA with the same disease as the last one and they don’t even last a day.

I tried treating with the triple antibiotic combo right when she went into QT, but that wasn’t enough. Scales and skin just slough off. It started on one side and spread throughout the body, and died in less than 10hr. Meanwhile there is a juvenile rhomboidalis that has zero symptoms.

 

[Big G]

Not seeing the "red sores" that usually accompany uronema. I'm leaning gram negative bacterial infection. It's an extremely quick killer and is not usually infectious, thus your other fish appears ok. The antibiotics used to treat can take quite awhile to do some good. Remember they don't "cure" they just help give the fish's immune system time to gear up and fight the infection. I've had really positive results using Nitrofuracine Green Powder (NFG). It seems to get into the fish's system quicker and more completely. Sorry for your losses.

From @Humblefish

Bacterial infections:

Symptoms - Sometimes it's self-describing: Popeye/cloudy eyes, fin & tail rot, dropsy (bloated fish), etc. But some other bacterial infections, such as furunculosis, hemorrhagic septicemia, etc., can have varying visible symptoms. Any redness or open sores/wounds on a fish should be viewed with suspicion. Also, a white film or fungus-looking growth may denote a bacterial infection. It’s important to note that in many cases a bacterial infection is usually secondary in nature to a parasitic infestation such as ich, meaning if a fish has been battling ich for a while then his immune system has been lowered. This makes infection more likely for many opportunistic, harmful bacteria.

Treatment options - Broad spectrum antibiotic medication i.e. one that treats both gram-positive and gram-negative bacterial diseases. Examples of this include Furan-2, Kanamycin aka Seachem Kanaplex, Nitrofuracin Green Powder, Triple Sulfa Powder, or a combination of using both Erythromycin & Minocycline. The latter can be accomplished (albeit expensively) by using freshwater Maracyn 1 & 2 and then doubling the dosage for saltwater use. When battling a particularly nasty bacterial infection, combining Furan-2, Kanaplex and metronidazole (ex. Seachem MetroPlex) can be very effective (and safe). Props to “hedgedrew” for enlightening me of this.

 

[Highgrade]

Seems like Uronema. https://www.reef2reef.com/threads/uronema-marinum.247940/

@Humblefish @melypr1985 might have input

 

[wangspeed]

I used the F2, K, M combo, but it still spread like wildfire. It was only on one side when she came in, and by the time of death just 8 hours later, it had spread to the other side. You can see missing scales and skin in that second picture.

 

[wangspeed]

Here’s the first lineatus. It has the more telltale red spot of uronema. Maybe a combination of the two? It’s just so fast!

 

[HotRocks]

I wouldn't rule out brook here either. Not super common in wrasse. Possible though.

Seems like Brook or bacterial. Gram negative bacterial infections are ugly, also common in "newly acquired fish".