Prazipro Help!!!

[osu87]

Hi I just started dosing Prazipro in my evo 13.5 reef DT. I have so many different things,

I have read wait seven days for the second dose. I have read weight eight days for the second dose. I have read wait 10 days for the second dose.

I have read some people say to do a third dose

Let me start out by saying I did turn off my small UV lightbulb and I took the cup off of my protein skimmer. I added an air stone. I have my power head going and my wave maker

I dosed a half a teaspoon and an eighth of a teaspoon.

I have read do a 25% water change after three days and also just before the second dosing. I have also read to put carbon back in and turn on your UV and protein skin more anywhere from 24 to 48 to 72 hours after dosing.

Can anyone help clarify this for me?

I am treating for flukes. My fish are eating just fine, but my royal drama is flashing. I have been watching him for days and none of the fish had any signs that I could tell of ich nor velvet. This is why I suspect flukes because the fish bodies look pristine otherwise.

 

[osu87]

Hi I just started dosing Prazipro in my evo 13.5 reef DT. I have read so many different things,

I have read wait seven days for the second dose. I have read wait eight days for the second dose. I have read wait 10 days for the second dose.

I have read some people say to do a third dose or 4th

Let me start out by saying I did turn off my small UV lightbulb and I took the cup off of my protein skimmer. I added an air stone. I have my powerhead going pointing upward and my wave maker going.

I wanted to make sure to have a lot of aeration because I do have a pink streak wrasse in there.

I dosed a half a teaspoon and an eighth of a teaspoon of Prazipro taking into account, my sand bed and rocks that I have probably 10 1/2 to 11 gallons of actual water Volume

I have read do a 25% water change after three days and also just before the second dosing. I have also read to put carbon back in and turn on your UV and protein skimmer anywhere from 24 to 48 to 72 hours after 1st dosing and turning all off again and take out carbon before next dose, and then some say not to do this until after the second dose.

Can anyone help clarify this for me? It is all so confusing.

I am treating for flukes. My fish are eating just fine, but my royal gramma is flashing/scratching. I have been watching him for days and none of the fish had any signs that I could tell of ich nor velvet. This is why I suspect gill flukes because the fish bodies and eyes look good otherwise.

 

[osu87]

Mods please delete. I posted in the correct area

 

[C_AWOL]

In a quarantine tank, I personally do 3 doses in total 7 full days apart from one another (for example a dose on monday would be re-dosed on tuesday then the following wednesday). Keep in mind, there's typically less biodiverity and biodensity (in terms of bacteria) in a quarantine tank so there's less worry about consumption of the solvents (or praziquantel itself) in prazipro as far as I'm aware.

In an actual display tank, it's likely that prazipro becomes inactivated much sooner due to the organic load which is why you may hear a dose rate of every 3 days and following such advice isn't an issue as long as you do water changes and keep in mind that only 2-3 doses at that frequency may not be enough to rid yourself of flukes due to their life cycle/hatch cycle (your goal is to basically catch all hatched flukes since eggs are unaffected)

If it's not too much work for you, have you done a freshwater dip to confirm flukes instead of it being early stages of ich?

 

[vetteguy53081]

Hi I just started dosing Prazipro in my evo 13.5 reef DT. I have read so many different things,

I have read wait seven days for the second dose. I have read wait eight days for the second dose. I have read wait 10 days for the second dose.

I have read some people say to do a third dose or 4th

Let me start out by saying I did turn off my small UV lightbulb and I took the cup off of my protein skimmer. I added an air stone. I have my powerhead going pointing upward and my wave maker going.

I wanted to make sure to have a lot of aeration because I do have a pink streak wrasse in there.

I dosed a half a teaspoon and an eighth of a teaspoon of Prazipro taking into account, my sand bed and rocks that I have probably 10 1/2 to 11 gallons of actual water Volume

I have read do a 25% water change after three days and also just before the second dosing. I have also read to put carbon back in and turn on your UV and protein skimmer anywhere from 24 to 48 to 72 hours after 1st dosing and turning all off again and take out carbon before next dose, and then some say not to do this until after the second dose.

Can anyone help clarify this for me? It is all so confusing.

I am treating for flukes. My fish are eating just fine, but my royal gramma is flashing/scratching. I have been watching him for days and none of the fish had any signs that I could tell of ich nor velvet. This is why I suspect gill flukes because the fish bodies and eyes look good otherwise.

We recommend eight days apart and good that you verified as we too see many doing 3-5-7 day intervals. Dose at 85% of recommended and apply initial dosage known as an interval for 8 days, do a water change and do one more 8 day dose interval
Use airstone with prazi as it does reduce both oxygen and appetite. If running a skimmer, leave cup off first 24 hrs as skimmer will go nuts from the glycol solution in Prazi. There are extreme cases that you will need more than two doses especially with flukes that leave eggs and which have to be addressed after normal treatment regimen

 

[Jay Hemdal Verified Community Expert]

Hi I just started dosing Prazipro in my evo 13.5 reef DT. I have so many different things,

I have read wait seven days for the second dose. I have read weight eight days for the second dose. I have read wait 10 days for the second dose.

I have read some people say to do a third dose

Let me start out by saying I did turn off my small UV lightbulb and I took the cup off of my protein skimmer. I added an air stone. I have my power head going and my wave maker

I dosed a half a teaspoon and an eighth of a teaspoon.

I have read do a 25% water change after three days and also just before the second dosing. I have also read to put carbon back in and turn on your UV and protein skin more anywhere from 24 to 48 to 72 hours after dosing.

Can anyone help clarify this for me?

I am treating for flukes. My fish are eating just fine, but my royal drama is flashing. I have been watching him for days and none of the fish had any signs that I could tell of ich nor velvet. This is why I suspect flukes because the fish bodies look pristine otherwise.

Because there is some confusion about praziquantel, I did some additional research over the last month and wrote up some notes:
https://www.reef2reef.com/threads/dosing-praziquantel-pzq.1105700/

 

[osu87]

We recommend eight days apart and good that you verified as we too see many doing 3-5-7 day intervals. Dose at 85% of recommended and apply initial dosage known as an interval for 8 days, do a water change and do one more 8 day dose interval
Use airstone with prazi as it does reduce both oxygen and appetite. If running a skimmer, leave cup off first 24 hrs as skimmer will go nuts from the glycol solution in Prazi. There are extreme cases that you will need more than two doses especially with flukes that leave eggs and which have to be addressed after normal treatment regimen

Thank you for that!!

 

[osu87]

Because there is some confusion about praziquantel, I did some additional research over the last month and wrote up some notes:
https://www.reef2reef.com/threads/dosing-praziquantel-pzq.1105700/

Thank you for posting.

 

[osu87]

I am happy to say everyone was ok today, my one fire shrimp seemed stunned yesterday but back to normal this morning, the other one and the cleaner did not nor did the mithrax crab, my pink streak wrasse was ok as was the royal gramma with the issue and my rainford goby.

So I will do a dose in 8 days

Should I do my water change in 3 days from initial dose??

Also should I put my skimmer cup back on at the 24 hour mark or 72 hour, same for UV and adding carbon until they go out again for 2nd dosing.?

Thanks for help.

 

[vetteguy53081]

I am happy to say everyone was ok today, my one fire shrimp seemed stunned yesterday but back to normal this morning, the other one and the cleaner did not nor did the mithrax crab, my pink streak wrasse was ok as was the royal gramma with the issue and my rainford goby.

So I will do a dose in 8 days

Should I do my water change in 3 days from initial dose??

Also should I put my skimmer cup back on at the 24 hour mark or 72 hour, same for UV and adding carbon until they go out again for 2nd dosing.?

Thanks for help.

Yes on skimmer cup
No carbon

 

[Jay Hemdal Verified Community Expert]

I am happy to say everyone was ok today, my one fire shrimp seemed stunned yesterday but back to normal this morning, the other one and the cleaner did not nor did the mithrax crab, my pink streak wrasse was ok as was the royal gramma with the issue and my rainford goby.

So I will do a dose in 8 days

Should I do my water change in 3 days from initial dose??

Also should I put my skimmer cup back on at the 24 hour mark or 72 hour, same for UV and adding carbon until they go out again for 2nd dosing.?

Thanks for help.

Water change and return the skimmer cup any time after 24 hours after the first dose.

 

[osu87]

Water change and return the skimmer cup any time after 24 hours after the first dose.

Thank you Jay

 

[osu87]

I returned my protein skimmer cup this evening and tomorrow I will do a water change. I left my UV light off and I did not put any carbon back in.

Monday, which will be day eight I will dose again this time with only half a teaspoon instead of half a teaspoon, + an eighth of a teaspoon as I think I forgot to take off for the fact that my water volume doesn’t fill to the brim of the aquarium even though I did account for the sand and the rock.

Then I assume my plan should be after 24 hours of dose number two I can then return the protein skimmer cup once again do a water change and then at that point should I turn back on my UV light bulb and add my activated carbon back to my filtration in my evo aio?

 

[bgervaisToronto]

I understand carbon dosing isnt a good idea but what about activated carbon? Put it back in at 72h?

 

[Jay Hemdal Verified Community Expert]

I understand carbon dosing isnt a good idea but what about activated carbon? Put it back in at 72h?

Yes, but you’ll need to remove it before any subsequent dose. Actually, you can add carbon after 36 hours.

 

[bgervaisToronto]

Same goes for uv then? Reading your recommendations, It seems over the years you have shorten your timeline on how long prazi is active. Would that be correct Jay?

 

[Jay Hemdal Verified Community Expert]

Same goes for uv then? Reading your recommendations, It seems over the years you have shorten your timeline on how long prazi is active. Would that be correct Jay?

Yes, same with UV. Just be aware that UV and chloroquine should never be done.

The treatment time for prazi is tricky to calculate - bacteria grows in tanks after the initial dose that eats prazi. Eventually, it consumes the prazi before it can really work.