Just a few years ago I performed TTM + Prazipro on all the fish for my personal tank: https://www.reef2reef.com/threads/humblefishs-150-gal-mixed-reef.189950/
I was primarily only worried about ich + flukes. Nowadays I wouldn't even consider that passive of a QT protocol. Things have changed.
Same here. That's all I used to do just to try and eliminate ICH and Flukes. Then if Velvet or brook popped up I'd treat it with Copper or Formalin.
Now days all my fish are FW dipped on day 1 and I follow that up with a 90 min bath of Acriflavine or a 50 min dip of Formalin. This just depends on fish species and what I feel like they need.
Then they go into a sterile medicated tank (Copper or CP) and Day 1 of the Transfers begins. I'll try to run API GC or Praziquantel with it depending on the primary medication.
I typically stick to the 3 day 72 hr rule for Transfers unless there's Velvet present.
If Velvet is present... it drops from 72 to every 48 hrs and possibly every 24 hrs if needed, and sometimes it's definitely needed to reduce numbers.
I try to start them eating API GC on Day 1, but this is proving to be next to impossible for some fish. So I will now switch over to food soaked Metro "alone" and see how that goes.
Before each transfer...I continue to dip the fish or do baths 1-2 hours before the transfers with either Acriflavine or Formalin.
If a Bacterial infection pops up...I start to runs ABX's. Of course making sure what's all currently in the tank is compatible.
You get the idea...a lot of treatments going on at my house.
Even with all this...I have still not been successful at eliminating URONEMA. ;Rage
It's OK though. I'm testing several things right now. Hopefully something will work. It's not the external parasites that I'm concerned with. It's the internal parasites.
I'm pretty sure that injecting the fish is the best and quickest way to conquer it.