Ty for detailed response.Work in a fish store. It's disheartening.
I believe that there is a lot of this.
I find that with new fish you struggle with two things.
The first and for me the most important is getting the fish eating. Most have not been feeding their entire journey and are timid with food. BTW this is not a wild behaviour, fish are pigs. You see this natural behaviour come back after you have had them for a while. Food is tough and most fish will try anything if they get really hungry. Getting them to eat after this is REALLY difficult. I would say that almost all of my new fish during this time end up with some sort of parasite or disease. They "scratch" a lot or have visible signs of infestation. After years of observing this phenomona I have finally learned to ignore it and focus on tank stability and ensuring the fish is eating. This can be incredibly nerve wracking because everything inside of us is screaming that we have to do something. This process is not easy, and I have found the more mature the tank the easier the process is.
The second is somewhat of an outcropping of the first. You need to deal with a fish that has been medicated every step of the journey (assuming you bought non-quarintined fish, and then they off load that burden from you for a price). This creates a creature that is not going to do very well being thrown back into a "natural" environment. Ensuring that the tank will help not hinder recovery takes some planning and patience, but I find doing this to be much easier and more successful than using quarintining with medication.
My 2 cents.
You work in a lfs so seen first hand amount of fish that die you say,my thinking is all stress from travelling half way around world from collectors-exporters-importers-lfs then to us,I find out when next delivery of fish will be at the lfs then go in and buy my fish on that day or day before so the newest fish in the tanks been in the lfs tanks 4-6 days and always ask when it came in with the thinking that that last bit if stress/ transport to lfs could be straw that broke camels back so to speak and make that fish ill or catch a parasatite easier so want to leave fish in lfs store as long as possible for signs to show ( ovbiously will large systems only takes one fish to have 1 parasite then travels through all tanks ) lfs I shop at now only has 3 tanks connected to each other but then there's lfs employees putting hands in and out of all tanks and possible cross contamination and no lfs I been in use 1 net for 1 tank ,its just pick up any net and use it lol
And the second part what you wrote ?
You mean if medicate the fish,you strip all its immunity from it then when put in dt it's more at risk of a diesese manages to slip through as now fish got no immunity? Or do I misunderstand you?