Nope never tried that. It won't hurt inverts/corals?
I think it has it's risks. The concentration would have to be low. So in terms of treatment, take it slow. People used to use it to raise pH and from my understanding it can raise sodium and alkalinity. It's water soluble but might be pasty at first. In regards to spot treatment, getting a little on bubble algae and letting it dissolve might be ok.
I never use more than 10 ml per 25 gallons.