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The PraziPro treatment would address flukes prophylactically, however if you suspect flukes...particularly a heavy infestation or flukes in the eyes; then doing a freshwater dip first to confirm/remove a large portion of the worms is recommended. When PraziPro hits the worms they seize and spasm, which can be very uncomfortable on a heavily afflicted fish.
^^ Agree; perfectly stated. :)

