Dosing Praziquantel (PZQ)

[TylerHaworth]

It's been five days so the third dose just went in. Hope this is working.

Planning on a fourth round in five more days.

 

[Bronco765]

Is there a way to know if the bacteria ate the Prazi before it was effective?

 

[Jay Hemdal Verified Community Expert]

Is there a way to know if the bacteria ate the Prazi before it was effective?

Nope - that requires HPLC in a lab. All we can do is observe the results and try to make an educated guess as to when prazi becomes degraded.

 

[Bronco765]

Is there a way to know if the bacteria ate the Prazi before it was effective?

Nope - that requires HPLC in a lab. All we can do is observe the results and try to make an educated guess as to when prazi becomes degraded.

The Semilarvatus looks a lot better today so it’s on the mend.

 

[LeftyReefer]

I've got a few fish in QT right now, that are just about done... They've been in copper power for 30 days and they have one more round of prazi to go.. 2 rounds of prazi have been done, 8 days apart.

I've always used the liquid prazipro in the past, but this time I've been using the prazi powder. (prazicleanse)
I will say, the powdered prazi seems much better than the prazipro as far as (not) feeding/causing
bacterial blooms. Every time I have used prazipro in the past, within a day or so, the tank is always cloudy and the fish seemed stressed.
I saw no such thing using the powder version. I never saw any type of bacterial bloom or cloudiness using the powdered prazi. Fish did not seem as stressed during the prazi treatments either.

I did have to use a fine mesh net like Jay suggested, to get it dispersed, but it actually wasn't difficult at all.

I also like that the Fritz Prazicleanse packets are pre-dosed for 20 gallons, which is great because I use a 20G QT tank. I'll be sticking with the powdered prazi from now on.

 

[Jay Hemdal Verified Community Expert]

I've got a few fish in QT right now, that are just about done... They've been in copper power for 30 days and they have one more round of prazi to go.. 2 rounds of prazi have been done, 8 days apart.

I've always used the liquid prazipro in the past, but this time I've been using the prazi powder. (prazicleanse)
I will say, the powdered prazi seems much better than the prazipro as far as (not) feeding/causing
bacterial blooms. Every time I have used prazipro in the past, within a day or so, the tank is always cloudy and the fish seemed stressed.
I saw no such thing using the powder version. I never saw any type of bacterial bloom or cloudiness using the powdered prazi. Fish did not seem as stressed during the prazi treatments either.

I did have to use a fine mesh net like Jay suggested, to get it dispersed, but it actually wasn't difficult at all.

I also like that the Fritz Prazicleanse packets are pre-dosed for 20 gallons, which is great because I use a 20G QT tank. I'll be sticking with the powdered prazi from now on.

Good to hear - I always use bulk prazi powder, the few times I've used prazi with a solvent, I've had issues. It's just that prazipro is so readily available.....

 

[Bronco765]

I've got a few fish in QT right now, that are just about done... They've been in copper power for 30 days and they have one more round of prazi to go.. 2 rounds of prazi have been done, 8 days apart.

I've always used the liquid prazipro in the past, but this time I've been using the prazi powder. (prazicleanse)
I will say, the powdered prazi seems much better than the prazipro as far as (not) feeding/causing
bacterial blooms. Every time I have used prazipro in the past, within a day or so, the tank is always cloudy and the fish seemed stressed.
I saw no such thing using the powder version. I never saw any type of bacterial bloom or cloudiness using the powdered prazi. Fish did not seem as stressed during the prazi treatments either.

I did have to use a fine mesh net like Jay suggested, to get it dispersed, but it actually wasn't difficult at all.

I also like that the Fritz Prazicleanse packets are pre-dosed for 20 gallons, which is great because I use a 20G QT tank. I'll be sticking with the powdered prazi from now on.

Good to hear - I always use bulk prazi powder, the few times I've used prazi with a solvent, I've had issues. It's just that prazipro is so readily available.....

If you’re not sure it’s gill flukes or Neonendenia flukes which would be best for the dosing schedule, 5 or 8 days?

 

[LeftyReefer]

If you’re not sure it’s gill flukes or Neonendenia flukes which would be best for the dosing schedule, 5 or 8 days?

I've just been using the standard intervals as recommended in Jay's current QT protocol thread which calls for prazi every 8 days +/-. My new fish have not shown any signs of having any flukes, so I'm just treating per the QT protocol which calls for prazi on 7-9 day intervals. If I suspected a certain type of fluke I would certainly want to take that into consideration.

 

[Bronco765]

If you’re not sure it’s gill flukes or Neonendenia flukes which would be best for the dosing schedule, 5 or 8 days?

I've just been using the standard intervals as recommended in Jay's current QT protocol thread which calls for prazi every 8 days +/-. My new fish have not shown any signs of having any flukes, so I'm just treating per the QT protocol which calls for prazi on 7-9 day intervals. If I suspected a certain type of fluke I would certainly want to take that into consideration.

I’ve started using the Prazicleanse also. I never liked Prazipro because of the solvent. Did you have to press the Prazicleanse through the net?

 

[LeftyReefer]

I’ve started using the Prazicleanse also. I never liked Prazipro because of the solvent. Did you have to press the Prazicleanse through the net?

Yes. the first time I pressed it through the net into a cup of RODI, and then dumped that into my QT tank.

the 2nd round of prazi, I just pressed it through the net directly into my QT tank and had to mixed it in a little.
both ways seemed to work fine. Although, if you have really stressed fish in your QT, adding it to a cup of RODI first would probably be the easiest way.

 

[Jay Hemdal Verified Community Expert]

If you’re not sure it’s gill flukes or Neonendenia flukes which would be best for the dosing schedule, 5 or 8 days?

Split the difference at 7 days, but you'll likely need at least three treatments.

 

[JumboShrimp]

What in the world has apparently happened to the 'world supply' of API General Cure? Last night the only way to buy it on Amazon was to buy a multiple-box bundle of about $100's worth... a record high price, per the pricing history... and many other places online and locally seem to be out of it.

I ordered a Fritz product 'equivalent', available in a single box for about $22.00.