I started doing the complete opposite of an apex and have come to a similar conclusion that a GLH approach will also best suit my needs. Initially I really wanted to avoid wires going everywhere and keep it as compact as possible so I was going for an AIO enclosure - 16 power outlets, Raspberry pi, probes, PWM etc. all together to minimise external wiring.
While putting my build together I have realised that it's not going to be as functional and compact as I would like and it's very hard to manage the wires internally when doing 16 AC outlets + everything else :p
I'm now planning on doing 2x 8 outlet power bars, a remote PWM module (to go up in my hood with the LED lights) and then a main hub for everything else (Raspberry pi, probes and anything else in the future).
I've had to order a few new parts so my build is on hold for a month or two while they arrive but it gives me time to play with my new 3D printer and see if I can design and 3D print the enclosures I need :)
Just a couple of days ago I made the decision to go with RJ-45 connectors. They are compact, clean and once you have the special crimp they appear very easy to do (might even be able to wire multiple float switches to 1 RJ-45 plug?)
The special crimp required almost put me off but I found one on ebay with a cable tester for only $11 which is next to nothing considering it will enable me to quite cheaply make multiple cables of different lengths to suit my needs. Then I was able to get 20 PCB mount female RJ-45 sockets and 20 male plugs with boots for $12. This should be more than enough to get me set up with current Reef-Pi capabilities with a few more for future expansion.
I'll also be using a small 240V AC - 5V DC buck converter inside each power bar enclosure with 8 outlets so I can power the 5v for the relay from that and then I can use all 8 of the RJ-45 wires for the 8 relay signals. That way each power bar will only have 2 cables going to it (AC plug and RJ-45). If I was going to do all 16 relays in one I could just put 2x RJ-45 sockets on it.
I wouldn't discount them completely as after the minor one off purchase of the crimp they appear quite functional to me.