That pH issue sounds like a common problem with hexadecimal vs base 10. That's a UI issue that I'd like to address at some point when I get some time to work on software again. i2cdetect is showing hex addresses (0x45), but reef-pi expects a base 10 address (69).
Technically, you can use the same i2c bus to communicate with additional sensors and peripherals, but reef-pi does not currently support those. On the other hand, you could run additional software on the rpi to supplement reef-pi's features.
I'd love to get into aquaponics one of these days. It would be pretty easy to extend reef-pi for that domain. I would definitely follow a build log on that if you start one.