Third time better be the charm

[EeyoreIsMySpiritAnimal]

Again, Cipro is not my go-to first line treatment for a number of different reasons, and I generally do not ever reccomend dosing antibiotics directly into a DT unless it is an absolute emergency. The exception being when treating Heteractis sp. For V. vulnificus auto innoculation. That being said, the dose is the dose in SW, regardless of the critter.

:thinking-face:.... Well other places say 0.5mg per gallon.

 

[Fish Styx]

:thinking-face:.... Well other places say 0.5mg per gallon.

 

[Fish Styx]

The thing about treating a DT is that, once you start antibiotics, you aren't just fighting what is infecting your critters. Every, and I mean EVERY one of our tanks has a host of nasty bugs such as V. vulnificus, A. hydrophila, group A strep, etc. You want to make sure that you kill that, too. Otherwise you ultimately end up inadvertently brewing a soup of antibiotic resistant superbugs. Trust me on this...

This is one of the reasons why I do not generally reccomend dosing a DT. If someone is going to, though, the effective dose is 50mg / gal QD x 7 - 10 days.

 

[MrsBugmaster]

50$ gift card raffle winner. Guess the universe wants me to get a new clown.

Yep!

 

[tbrown]

 

[JoJosReef]

The thing about treating a DT is that, once you start antibiotics, you aren't just fighting what is infecting your critters. Every, and I mean EVERY one of our tanks has a host of nasty bugs such as V. vulnificus, A. hydrophila, group A strep, etc. You want to make sure that you kill that, too. Otherwise you ultimately end up inadvertently brewing a soup of antibiotic resistant superbugs. Trust me on this...

This is one of the reasons why I do not generally reccomend dosing a DT. If someone is going to, though, the effective dose is 50mg / gal QD x 7 - 10 days.

But dangerous isn't it, since different bugs require different dosing for efficacy. The dose for Arcobacter could be way lower than that required for Grp A strep. Ultimately, though, I can only imagine risk of a superbug leaving a tank and becoming a public health problem is super miniscule... That said I heard of someone carrying Vibrio out of their tank, so...

 

[Fish Styx]

But dangerous isn't it, since different bugs require different dosing for efficacy. The dose for Arcobacter could be way lower than that required for Grp A strep. Ultimately, though, I can only imagine risk of a superbug leaving a tank and becoming a public health problem is super miniscule... That said I heard of someone carrying Vibrio out of their tank, so...

Yeah, that guy sucks...

 

[Fish Styx]

But dangerous isn't it, since different bugs require different dosing for efficacy. The dose for Arcobacter could be way lower than that required for Grp A strep. Ultimately, though, I can only imagine risk of a superbug leaving a tank and becoming a public health problem is super miniscule... That said I heard of someone carrying Vibrio out of their tank, so...

The bigger danger, IMO, is crashing the biofilter. Though there are many far more knowledgeable than myself that feel that that isn't too much of a concern when dosing a DT. I remain skeptical.

 

[JoJosReef]

The bigger danger, IMO, is crashing the biofilter. Though there are many far more knowledgeable that myself that feel that that isn't too much of a concern when dosing a DT. I remain skeptical.

Dose is a big factor. As long as the mechanism is relevant to the bug's metabolism or replication, pumping up the dose will eventually kill it (and a lot of other stuff). So, I'm *imagining* that a low dose DT treatment like the author of the BJD treatment thread suggests, won't knock out everything. I have no idea if ammonia oxidizing and nitrite oxidizing bacteria have the same DNA gyrases that are targeted by cipro in typical human pathogens--although I *imagine* they are highly conserved even between these very different bacteria. I do a lot of *imagining* because I can't be bothered to pull the papers myself :~)

 

[Fish Styx]

Dose is a big factor. As long as the mechanism is relevant to the bug's metabolism or replication, pumping up the dose will eventually kill it (and a lot of other stuff). So, I'm *imagining* that a low dose DT treatment like the author of the BJD treatment thread suggests, won't knock out everything. I have no idea if ammonia oxidizing and nitrite oxidizing bacteria have the same DNA gyrases that are targeted by cipro in typical human pathogens--although I *imagine* they are highly conserved even between these very different bacteria. I do a lot of *imagining* because I can't be bothered to pull the papers myself :~)

I *imagine* that you are largely correct. I still maintain that antibiotic treatment in general, but flouroquinalone treatment especially, in the DT is one of last resort, because low dose treatment is not sufficient to avoid antibiotic resistance in what can infect humans. Also, through water changes, it needs to be dumped and subsequently introduced into our waste water.

 

[Stang67]

I would spend my whole pocket on just mystery ones. I'm terrible like that.

I got 3 but ended up with 5. Would highly recommend. All the offerings were top notch and very nice quality. Will definitely be saving up for more.

 

[EeyoreIsMySpiritAnimal]

You got it. I'm going to have quite a bit to bring in June by the way things are going.

What's in June?

 

[Stang67]

The bigger danger, IMO, is crashing the biofilter. Though there are many far more knowledgeable that myself that feel that that isn't too much of a concern when dosing a DT. I remain skeptical.

about crashing the whole bio filter is my concern. I was graciously given some tabs of cipro today by @Aqua62 along with some other awesome goodies. I am holding them in reserve in the event anything else shows issues.

 

[Stang67]

What's in June?

Pup/house sitting for my parents in Indianapolis for 2 wks.

 

[JoJosReef]

I *imagine* that you are largely correct. I still maintain that antibiotic treatment in general, but flouroquinalone treatment especially, in the DT is one of last resort, because low dose treatment is not sufficient to avoid antibiotic resistance in what can infect humans. Also, through water changes, it needs to be dumped and subsequently introduced into our waste water.

I'm in favor of adding bleach to water change waste up to 10% for half an hour before dumping!

 

[JoJosReef]

about crashing the whole bio filter is my concern. I was graciously given some tabs of cipro today by @Aqua62 along with some other awesome goodies. I am holding them in reserve in the event anything else shows issues.

Hopefully you don't need them!

 

[Stang67]

OK so the haul was massive. I will say that the coolest thing is something I have been on the look out for for a while now. I spent way to much but I HAD TO HAVE IT. Chandler Rocks Aquascaping. Beautiful stuff.

Then with my winning gift card I got a Darwin Clown for the main display to replace Bonnie, and a Mocha clown to put up in the office tank. Pics of them soon.
Then for the corals.
Cherry corals (my favorite) grabbed a Tsa Bill Murry and a Cc Mai Tai. From Camero ended up with 2 zoas, a goni, a favia and a Tgc surprise attack. Then my stuff off reef trader and @Aqua62.
Better pix soon. At mans house tonight utterly exhausted.

 

[EeyoreIsMySpiritAnimal]

Pup/house sitting for my parents in Indianapolis for 2 wks.

I hope it's not during the time I'll be in CLEVELAND!!

 

[Fish Styx]

OK so the haul was massive. I will say that the coolest thing is something I have been on the look out for for a while now. I spent way to much but I HAD TO HAVE IT. Chandler Rocks Aquascaping. Beautiful stuff.

Then with my winning gift card I got a Darwin Clown for the main display to replace Bonnie, and a Mocha clown to put up in the office tank. Pics of them soon.
Then for the corals.
Cherry corals (my favorite) grabbed a Tsa Bill Murry and a Cc Mai Tai. From Camero ended up with 2 zoas, a goni, a favia and a Tgc surprise attack. Then my stuff off reef trader and @Aqua62.
Better pix soon. At mans house tonight utterly exhausted.

TGC Surprise Attack is a nice find!

 

[steveschuerger]

I’ve used cipro a couple times, but only after seeing signs of BJD on my Euphyllids or Gonis , both of whom seem to the most likely to get it. I do have some that I got as back up for emergencies and chemiclean as well. I’m actually doing a run of chemi as we speak. Never had any negative issues with either but yeah I try not to use them unless absolutely necessary.