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It is no secret that gut bacteria is what controls our immunity and a fish. To expect a fish to live for five years is a total failure as a fish should only die of old age and never anything else. Absolutely any other cause of death is a total failure.
Most of our fish should live 15 or 20 or more years, I know some of yours do.
Paul, there's no direct evidence that chemoprophylaxis shortens the life span of fish. At least not the meds we're advocating. And even if the fish did only live for 5-10 years due to chemoprophylaxis, that's a heck of a lot better than, "OMG all my fish are dying from velvet." Which is what happens when most newbies forgo QT.
You forget I used to be on the other side of this argument for almost 30 years. But I had my father there to show me all the little tricks he employed so he wouldn't have to QT. Velvet, brook, uronema and other virulent diseases were also not as common back then. Ich is pretty easy to beat. Around 10 years ago I decided if I was going to advocate quarantining, then I would need to practice what I was preaching.