We have 20 year established reef tank with hang on skimmer and canister filter the balance with the DSB has never been a problem but more likely a benefit to natural sea bed creation for longevity of tank. I have never tested other than salinity at water changes and have never had a problem.The big difference between promoting denitrification or the assimilation of nitrogen ( vodka, nopox, algae scrubber), in a closed system using a skimmer, is the fact the nutrient balance ( N ratio) can be restored by denitrification, not by assimilation.
A SB of +- 2 cm may have about the same denitrification capacity as a DSB without the risks involved.
As a DSB is a passive method, nothing can be managed. The denitrification capacity is unknown and limited.
If I have the need for removing a lot of safely stored nitrogen considered not needed I prefer to use active denitrification, giving the possibility for managing the removal rate.