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Please note, your LR will absorb the medication. I dosed my full system and at a lower level and it has taken over 2 months to remove the medication from my system. So each rock you dose will release the medication into your main system. I replaced well over 2x my system total gallons, I tried a UV light and carbon. Not sure if my carbon wasn't the best, but recently I switched to using the ROX carbon from BRS. I was finally able to add my sensitive corals back into my system. You may want to dose all your rocks in the smaller tank and then do large water changes and carbon before you add the rocks back to your main system.