General Cure treatment

[jmichaelh7]

Im dosing General cure by API for flukes. On the box it says wait 48 hours then dose again.

When reading online from other resources like Humble fish I see it says wait 5-7 days then re dose.

What is everyones dosing protocol for general cure ? I don’t want to apply more packets than needed on day X if I don’t need to. I have wrasse that are sensitive and doing fine.

also , do you usually keep skimmer on ?

 

[Jay Hemdal]

Im dosing General cure by API for flukes. On the box it says wait 48 hours then dose again.

When reading online from other resources like Humble fish I see it says wait 5-7 days then re dose.

What is everyones dosing protocol for general cure ? I don’t want to apply more packets than needed on day X if I don’t need to. I have wrasse that are sensitive and doing fine.

Yeah, the package is correct for the metronidazole it contains, but it is wrong for the praziquantel. Metro is often dosed every 48 hours to control protozoans, but the interval for praziquantel needs to be 8 days in order to break the life cycle of any fluke eggs - prazi doesn't kill fluke eggs, so you need to give them time to hatch and then try to kill those flukes before they have a chance to lay eggs of their own.

Same issue with trying to use General Cure orally - don't do it! The two drugs have two different oral dosages.

Jay

 

[vetteguy53081]

Im dosing General cure by API for flukes. On the box it says wait 48 hours then dose again.

When reading online from other resources like Humble fish I see it says wait 5-7 days then re dose.

What is everyones dosing protocol for general cure ? I don’t want to apply more packets than needed on day X if I don’t need to. I have wrasse that are sensitive and doing fine.

General cure has a low dosage of both praziquantel and metronizadole. It is not highly effective and I would recommend switching to PraziPro which is proven effective and is praziquantel.
manufacturer suggests 1 packet per 10 gallons for two days and is the one i would follow but again is a basic fluke treatment.
With Prazi pro, one application is good for 8 days and you will do a water change and apply one more application

 

[jmichaelh7]

General cure has a low dosage of both praziquantel and metronizadole. It is not highly effective and I would recommend switching to PraziPro which is proven effective and is praziquantel.
manufacturer suggests 1 packet per 10 gallons for two days and is the one i would follow but again is a basic fluke treatment.
With Prazi pro, one application is good for 8 days and you will do a water change and apply one more application

Why do you say it’s not highly effective ? The prazi dosage is low but from what I read it appropriate for sensitive fish like wrasse who do not do well with prazi.

You recommend folllowing the API 2 days then dose again on day 2 for flukes ?

I have a bottle of Prazipro but I also have had terrible results with Wrasses. I refrain from using it

 

[jmichaelh7]

Yeah, the package is correct for the metronidazole it contains, but it is wrong for the praziquantel. Metro is often dosed every 48 hours to control protozoans, but the interval for praziquantel needs to be 8 days in order to break the life cycle of any fluke eggs - prazi doesn't kill fluke eggs, so you need to give them time to hatch and then try to kill those flukes before they have a chance to lay eggs of their own.

Same issue with trying to use General Cure orally - don't do it! The two drugs have two different oral dosages.

Jay

Thank you Jay. What about using a skimmer ? The water is getting dirty visibly I’m wondering about turning on skimmer during the prazi treatment

 

[vetteguy53081]

Why do you say it’s not highly effective ? The prazi dosage is low but from what I read it appropriate for sensitive fish like wrasse who do not do well with prazi.

You recommend folllowing the API 2 days then dose again on day 2 for flukes ?

I have a bottle of Prazipro but I also have had terrible results with Wrasses. I refrain from using it

I ran an errand and see jay answered

 

[Colton Yuchnewicz]

i agree with all the above! and not related to your question, prazipro is excellent for flukes!

 

[jmichaelh7]

I ran an errand and see jay answered

i agree with all the above! and not related to your question, prazipro is excellent for flukes!

Run a Skimmer … no ?

 

[vetteguy53081]

Run a Skimmer … no ?

If you do, take collection cup off for first 24 hours

 

[Colton Yuchnewicz]

Run a Skimmer … no ?

taking the collection cup off helps oxygenate the water to assist with the meds. if i remember correctly. when i used prazi pro multiple times i never used a skimmer.

 

[jmichaelh7]

If you do, take collection cup off for first 24 hours

taking the collection cup off helps oxygenate the water to assist with the meds. if i remember correctly. when i used prazi pro multiple times i never used a skimmer.

I see . So the point is I’m trying to pull some of the inorganics out . I can tell the water without carbon and skimmer is getting dirty and waiting another 8 days is doable but at what point of water quality for the fish. If I put the cup back on then the meds will obviously get pulled I’m assuming

 

[vetteguy53081]

I see . So the point is I’m trying to pull some of the inorganics out . I can tell the water without carbon and skimmer is getting dirty and waiting another 8 days is doable but at what point of water quality for the fish. If I put the cup back on then the meds will obviously get pulled I’m assuming

Its the first 24 hours with cup off as prazi has a glycol agent which you dont want broken down too quickly. You can place cup back on next day

 

[Jay Hemdal]

Thank you Jay. What about using a skimmer ? The water is getting dirty visibly I’m wondering about turning on skimmer during the prazi treatment

You should run your skimmer, for the extra aeration, but don’t collect the skimmate because that will pull the prazi out.
Jay