I've
been posting this for quite a while. ;)
SRAC 4705: Amyloodinium ocellatum, an Important Parasite of Cultured Marine Fish
It's a good stand alone article, but of course (as I do) check the relevant references and go to Google Scholar from there for more.
If you have access to Noga's "Fish Disease..." book, he covers it as well...again, continue from there to Google Scholar if you need more.
I gave up on this a while back due to apparent lack of interest, but it has lots of great links. I may have to start updating it again if there's a way to get edit access.
Not sure I know the reference you mean. BTW, calling it "Ich" is confusing at this level of conversation IMO – Crypto, or Cryptocaryon are better since they will generate more meaningful search results for people.
IMO I think we're often better off being ambiguous about whether it's Crypto or Velvet vs. acting more certain than we really are. Ich/velvet are never positively ID'd by hobbyists, and they are substantially similar in lifestyle, symptoms and treatment.
Seems like folks default to talking about velvet since it's slightly nastier....and that mostly works.
So primarily I would suggest seeing doc# 4705 linked above (regarding velvet), and the references therein. All good solutions are discussed. Hit Google Scholar from there as needed.
If you wanna focus on Ich, this is my usual online go-to:
FA164/FA164: Cryptocaryon irritans Infections (Marine White Spot ... It's a good baseline, though it doesn't mention dips or peroxide. Anyhow,
these folks got up to 91% kill rate with peroxide (they did even better with an herbal).
Point being for us is that 100 ppm h2o2 was the highest concentration dip that was tested in that study. Folks in other studies (on velvet) are using higher h2o2 concentrations than that (100-300 ppm if I recall correctly), so ich would fall to those same treatments. (See link in next section.)
Again, doc #4705 posted above contains references for this to start you off. I do recommend reading the whole thing though.
A newer ref with a lot more detail, including baths, peroxide and A LOT more:
5. Amyloodiniosis in Semi-Intensive Aquaculture. This is a GREAT adjunct to doc 4705. Table 1 toward the end of section 4 is gold.
If someone doesn't want to read those links....a freshwater dip is used to provide immediate relief by removing attached swarmers.
Freshwater dips can be used strategically, almost as-needed. Unlike most meds, there's almost no stress involved (be gentle, avoid nets and avoid air exposure – not hard in most cases)*, so there's no reason NOT to do a dip at the first sign of an issue, depending on the exact scenario. I've dipped a LOT of common marine fish with virtually no side effects whatsoever – a few panic instances (mentioned before, not really a big deal) and one instance where I forgot to dechlorinate. MANY, MANY event-free dips tho. I specifically remember dipping a LOT of Tangs, quite a few Triggers, but many others.
Funny how freshwater dips get considered exotic and "harsh" around and at the same time we're all willy nilly and free with formalin and copper, which are both hard to use and verifiably deadly to the fish if used even slightly wrong. Chelated copper is slightly better, but also slightly less effective and less tested as well.
Noga, and probably other major sources go into these cautionary details because they are important for risk assessment. Water is not as dangerous as formalin or copper – duh, right?! I don't read every conversation online, but I never seem to see these points brought up when Formalin or Copper is being recommended or used. Dips in freshwater have no such problem.....anyone can do one and they're about as close to foolproof as you can get. (Just don't forget to dechlorinate the tap water.....I forgot that once. Once.)
Well, Ruby Reef is a company...but as far as I know they specialize in coral-safe/tank-safe products: Rally and Kick Ich. I admit it's my assumption that they are
herbal treatments...I may have heard that somewhere, but I don't remember where. (What I do know is that I've used most of them in retail and they seem to function as advertised.

)
Hydroplex is the exception – it's a dip; not tank safe, and I haven't used it personally yet.
Hm....I don't know if looking at it that way is helpful.
We aren't looking to UV to cure clinically infected fish. Ozone does work vs diseases per the literature (I think Jay speculated the action is similar to peroxide in another thread), but it's pretty uncommon in our wing of the hobby, at least in my experience....literally never seen an ozone generator in person, for sale or otherwise.
Makes no sense to me why UV (still) isn't better understood and used more widely – as far as I can tell, it's a very old, established technology....yet it gets treated like it was snake oil. Very odd. Consider that pest algae dino's are dino's and velvet are also dino's......UV works great for the former,
even with the janky setups people tend to use. There's no reason to assume things would be very different for parasitic dino's.
Put it another way for UV and similar: Under what circumstance would you want to give up your control on the situation and purposefully expose your fish to the full brunt of the possible parasite load? Controlling water parameters is good for up to 20% reduction. UV is good for 80+% reduction. Micron, ozone and the rest just take the control percentage higher and higher toward 100% control. Medicinal remedies don't need to come out until the immune systems are obviously not winning the battle anymore.....being observant, it's not hard to discern when a fish is going uphill or downhill – improving or not.
Spotte makes a good point about this in "Captive Seawater Fishes..." The fish gets sick because its immune system gets shut down by his own stress responses. Stresses like parasite load matter. (So does everything else – stress is cumulative.)
Velvet (Amyloodinium) infections in fish can easily be avoided. is another good article – they used a very comprehensive control system.
Glad I'm not the only one who sees that. ;)
That blurring goes along with this madness of assuming all fish are sick whether they show it or not (eliminating the concept of clinical and subclinical) and treating them regardless of their actual condition. If med's were a miracle cure, then that might make sense. But med's are not a miracle cure any more than anything else is.
Of course, this "lack of miracles" is exactly why a comprehensive approach is required on these matters.
Simply treating with meds is not doing anything to move toward "comprehensive". No more comprehensive than
doing nothing or just using UV, only with the added risk and toxicity stress that comes from the meds themselves.
Not talking about meds as part of a comprehensive strategy....In a comprehensive strategy the added stress and risk are much more accounted for.
I'm glad BTW that I at least occasionally see people chime in to say they got fish successfully through "standard QT" because IMO
that is a miracle. I'm also glad chelated copper has become more common as it's safer and harder to do wrong......but all the sources say it's also not as effective as old-school copper. "Eradication" is a word that gets thrown around very confidently, but I'm not sure that's actually possible....sources seem to always hedge (eg) that even copper can leave some alive. Just reinforces that there are no miracle cures.
Sorry this got so long.....tell me if I forgot to address anything you asked about. :)