There is info all over the place on how to use Ozone but like everything else in this hobby all information is subjective as we all have different tanks with different loads and we like different music.
Many people run it in a skimmer then run the effluent over carbon to eliminate residual ozone. I don't like carbon so I have a 5' trough over my tank filled with various corals, algae etc that the effluent runs over which would eliminate any ozone. That way I can run it at full strength. Everyone will argue as to what it does or does not do for your water quality so you will not get any exact answers. I have run it for about 40 years and so far I have no problems with anything but that could just be because of my good looks and have nothing to do with ozone.
But what it does is oxidize any organic molecule it contacts and we have plenty of organics in a reef. So in that respect it "may" slow down the accumulation of nitrates because bacteria feed on organics and the ozone will eliminate some of it. That is why bacteria hate ozone.
Many people run it in a skimmer then run the effluent over carbon to eliminate residual ozone. I don't like carbon so I have a 5' trough over my tank filled with various corals, algae etc that the effluent runs over which would eliminate any ozone. That way I can run it at full strength. Everyone will argue as to what it does or does not do for your water quality so you will not get any exact answers. I have run it for about 40 years and so far I have no problems with anything but that could just be because of my good looks and have nothing to do with ozone.
But what it does is oxidize any organic molecule it contacts and we have plenty of organics in a reef. So in that respect it "may" slow down the accumulation of nitrates because bacteria feed on organics and the ozone will eliminate some of it. That is why bacteria hate ozone.