Prazipro treatment

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I dosed prazipro yesterday. I turned off the pump and let it sit in my sump for a few hours. Today I've noticed the fish are a bit more aggressive towards each other. The sailfin has checked the vlamingii several times, the Carkii are mega d**KS. The female was after my bt trigger. The foxface was doing weird swimming and kept running into things. The foxface also had cloudy "slime" floating behind its eyes. He is why I did prazipro, eyes were cloudy when all others were not. I managed to catch him and he's in qt.
So is the prazi creating an uncomfortable situation for the others as they are infected with flukes as well? How do I keep them from being reinfected in the dt?
 
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I dosed prazipro yesterday. I turned off the pump and let it sit in my qt for a few hours. Today I've noticed the fish are a bit more aggressive towards each other. The sailfin has checked the vlamingii several times, the Carkii are mega d**KS. The female was after my bt trigger. The foxface was doing weird swimming and kept running into things. The foxface also had cloudy "slime" floating behind its eyes. He is why I did prazipro, eyes were cloudy when all others were not. I managed to catch him and he's in qt.
So is the prazi creating an uncomfortable situation for the others as they are infected with flukes as well? How do I keep them from being reinfected in the dt?
If you could send a picture that would be nice. I would wonder if it could be a bacterial infection as compared to fluke. Any other symptoms? Are you sure you dosed the Prazipro correctly for the volume in your tank? Do any of your fish have any other disease symptoms (beyond what you described - fast breathing, etc - were the rest of them quarantined)? Lastly you need to increase oxygen with Prazipro.
 
I dosed prazipro yesterday. I turned off the pump and let it sit in my qt for a few hours. Today I've noticed the fish are a bit more aggressive towards each other. The sailfin has checked the vlamingii several times, the Carkii are mega d**KS. The female was after my bt trigger. The foxface was doing weird swimming and kept running into things. The foxface also had cloudy "slime" floating behind its eyes. He is why I did prazipro, eyes were cloudy when all others were not. I managed to catch him and he's in qt.
So is the prazi creating an uncomfortable situation for the others as they are infected with flukes as well? How do I keep them from being reinfected in the dt?
How did you dose it and turning off the pumps was not good as Prazi has a glycol agent in the solution and needs to be diluted. The question is are they going nuts from solution, or is it because they are in a smaller tank being the quarantine tank with less cover.
The typical treatment for prazi is to be safe , dose at 80% of recommended and apply initial dosage known as an interval for 8 days, do a water change and do one more 8 day dose interval
Use airstone with prazi as it does reduce both oxygen and appetite
 
I need to go back and edit. I dosed it in my sump and let it dissipate for a couple hours. Then ran the tank as usual.
 
There isn't anything about a prazi treatment that would make the fish more aggressive.

I'm not sure about the turning off the sump - no need to do that. Prazipro actually disperses as a fine suspension - it is best to add some to the sump and the rest to the tank itself. Always add extra aeration when dosing, and dose to the net volume of the tank, not its rated capacity. Here is the instructions I give for its use:

Prazipro
You can dose your DT with Prazipro, when done properly, it is safe for fish and invertebrates (clams may retract a bit during treatment, there are rare reports of feather duster worms being harmed). The dose works like this: Remove all chemical filtrants like carbon. Add an extra air stone to the tank. Run any protein skimmers, but don't collect the skimmate. Add a full dose of Prazipro to the net volume of the tank (usually about 85% of the "rated" tank volume). Wait 8 days, change 25% of the water and redose. Praziquantel breaks down in about 72 hours, the water change is just to reduce nutrients leftover from that.

Jay
 
There isn't anything about a prazi treatment that would make the fish more aggressive.

I'm not sure about the turning off the sump - no need to do that. Prazipro actually disperses as a fine suspension - it is best to add some to the sump and the rest to the tank itself. Always add extra aeration when dosing, and dose to the net volume of the tank, not its rated capacity. Here is the instructions I give for its use:

Prazipro
You can dose your DT with Prazipro, when done properly, it is safe for fish and invertebrates (clams may retract a bit during treatment, there are rare reports of feather duster worms being harmed). The dose works like this: Remove all chemical filtrants like carbon. Add an extra air stone to the tank. Run any protein skimmers, but don't collect the skimmate. Add a full dose of Prazipro to the net volume of the tank (usually about 85% of the "rated" tank volume). Wait 8 days, change 25% of the water and redose. Praziquantel breaks down in about 72 hours, the water change is just to reduce nutrients leftover from that.

Jay
Thank you! Everyone is normal today. I did manage to get the foxface in qt. I didn't like how his eyes looked. He's also too skinny so I'll get to fatten him up too. (Waters green from Rally. Pics from a month ago)
 

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Back again. I did a 2nd dose of prazipro a half hour ago, and got the same behaviors. The vlamingii is all over the sailfin. I have the octoreef 150 running with the cup off
Fairy wrasse is in qt with the foxface. So out of harms way. The cloudiness is gone from his eyes and he did not enjoy me interrupting his bedtime.
20230526_231528.jpg
https://youtube.com/shorts/S5IC6MD-Ic8?feature=share
 
A couple of pics. I was worried about the white spots. I thought they were pretty normal, but since I'm all worried now...
20230526_233049.jpg
 

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I didn't see much with the Naso except it is breathing really hard. Did you add good aeration to the main tank itself?

Jay
 
There isn't anything about a prazi treatment that would make the fish more aggressive.

I'm not sure about the turning off the sump - no need to do that. Prazipro actually disperses as a fine suspension - it is best to add some to the sump and the rest to the tank itself. Always add extra aeration when dosing, and dose to the net volume of the tank, not its rated capacity. Here is the instructions I give for its use:

Prazipro
You can dose your DT with Prazipro, when done properly, it is safe for fish and invertebrates (clams may retract a bit during treatment, there are rare reports of feather duster worms being harmed). The dose works like this: Remove all chemical filtrants like carbon. Add an extra air stone to the tank. Run any protein skimmers, but don't collect the skimmate. Add a full dose of Prazipro to the net volume of the tank (usually about 85% of the "rated" tank volume). Wait 8 days, change 25% of the water and redose. Praziquantel breaks down in about 72 hours, the water change is just to reduce nutrients leftover from that.

Jay
I just added my first dose of Prazipro this morning for flukes. Question: If Prazipro breaks down in about 72 hours is it OK to turn off the air stone after 72 hours or should it remain on for the full 8 days? I ask because my fish are annoyed (or afraid) of the air stone and remain in hiding whenever it is running….so I’d like to turn it off as soon as it is safe to do so.
 
I just added my first dose of Prazipro this morning for flukes. Question: If Prazipro breaks down in about 72 hours is it OK to turn off the air stone after 72 hours or should it remain on for the full 8 days? I ask because my fish are annoyed (or afraid) of the air stone and remain in hiding whenever it is running….so I’d like to turn it off as soon as it is safe to do so.

It is the solvent used with Prazipro that gets broken down by bacteria, which in turn depletes the oxygen in the water. If your tank has a good protein skimmer, you can use that for aeration, just run it without collecting the skimmate. If you have a sump, you can put an air stone in there. The breakdown takes about 72 hours...

I find that aquarists now days tend to under aerate their tanks, not sure why. I run air lines in all my tanks to help ensure good gas exchange. They also help in cases where a pump fails - the air line can keep the fish alive until I notice the pump has failed.

Jay
 
It is the solvent used with Prazipro that gets broken down by bacteria, which in turn depletes the oxygen in the water. If your tank has a good protein skimmer, you can use that for aeration, just run it without collecting the skimmate. If you have a sump, you can put an air stone in there. The breakdown takes about 72 hours...

I find that aquarists now days tend to under aerate their tanks, not sure why. I run air lines in all my tanks to help ensure good gas exchange. They also help in cases where a pump fails - the air line can keep the fish alive until I notice the pump has failed.

Jay
Jay, so you run an air stone in a reef tank? I’ve often wondered about this. I only run my skimmer when my PH is below 8.4, which is about 15 hours a day. My display is a washing machine with 3 closed loops with a LiFePo4 5 day battery back up system in play. But, Murphy is a real person. Due to my washing machine life style, I battle salt spray on all my cross braces badly. So I am not really wanting to create more spray above the display. I have to scrap my cross braces with a razor weekly as it is very very noticeable with a par meter. I can put a meaning full amount of air bubbles into my sump, before my bubble trap. Will doing this be sufficient for a redundant back up plan? I can have this turn on when my skimmer is off or if my system senses it has shifted to my LiFePo4 system.
 
Jay, so you run an air stone in a reef tank? I’ve often wondered about this. I only run my skimmer when my PH is below 8.4, which is about 15 hours a day. My display is a washing machine with 3 closed loops with a LiFePo4 5 day battery back up system in play. But, Murphy is a real person. Due to my washing machine life style, I battle salt spray on all my cross braces badly. So I am not really wanting to create more spray above the display. I have to scrap my cross braces with a razor weekly as it is very very noticeable with a par meter. I can put a meaning full amount of air bubbles into my sump, before my bubble trap. Will doing this be sufficient for a redundant back up plan? I can have this turn on when my skimmer is off or if my system senses it has shifted to my LiFePo4 system.

Yes, I always have some secondary aeration device in every system - that was I won't lose fish overnight due to a pump failure. Also, people avoid aeration due to salt spray, but that isn't always in the fish's best interest, just yours. If you have a good skimmer on the system, run by a second pump, that can work as well.

You just need to evaluate your own system:

1) Is there some point in the system where water is being vigorously aerated for proper gas exchange?
2) If any single pump were to fail, would the fish be o.k. for 12+ hours?
 

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